The Cascapédia River is a river in the Gaspé Peninsula of Quebec which rises in the Chic-Choc Mountains and empties into Baie de la Cascapédia, a small bay on Baie des Chaleurs. The river is about 120 km in length.
It is known for its Atlantic Salmon fishing. Several Governors General of Canada, including The Marquess of Lansdowne and Lord Stanley, had summer homes along this river.
There is also the Petite Cascapédia River which empties into the same bay.